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Orum Therapeutics
Lexington
Job Description Job Description Salary: General Summary The CMC position will be based in Lexington, MA, and will play a key role in the progression to IND and beyond for Orum’s clinical products. This role requires the candidate to lead the company’s CMC efforts, including a combination of (1) setting the overall direction of the CMC activities a
Job Source: Orum Therapeutics1910genetics
Boston, MA, United States
1910 Genetics is the only company that has built a synergistic, dual-purpose small and large molecule platform that integrates artificial intelligence (AI), computation, and biological automation to design drug-like molecules better, faster, and cheaper than traditional approaches.Based in the Seaport District of Boston, 1910 Genetics is a Series A
Job Source: 1910geneticsNuvalent, Inc.
Cambridge, MA, United States
The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and
Job Source: Nuvalent, Inc.Avalyn Pharma Inc
Cambridge, MA, United States
Job Description Job Description Benefits: 401(k) matching Bonus based on performance Competitive salary Dental insurance Health insurance Paid time off Parental leave Stock options plan Training & development Tuition assistance Vision insurance Wellness resources Director/Sr. Director, Clinical Development Company Overview: Avalyn Pharma is de
Job Source: Avalyn Pharma IncJnana Therapeutics
Boston, MA, United States
Director/Sr. Director, Medicinal Chemistry About Us Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class the
Job Source: Jnana Therapeutics1910genetics
Boston, MA, United States
Director/Sr. Director of Search & Evaluation 1910 Genetics is the only company that has built a synergistic, dual-purpose small and large molecule platform that integrates artificial intelligence (AI), computation, and biological automation to design drug-like molecules better, faster, and cheaper than traditional approaches.Based in the S
Job Source: 1910geneticsJnana Therapeutics, Inc.
Boston, MA, United States
About Us Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, in
Job Source: Jnana Therapeutics, Inc.Amazon
Reading, MA, United States
Job ID: 2508309 | Amazon.com Services LLC Blink’s Marketing team is looking for a talented, innovative designer and art director with exceptional creative skills and a relentless desire to delight customers across a range of global design initiatives. This role will be customer obsessed and will always be innovating! They have proven expertise des
Job Source: AmazonBoston, MA, United States
Director/Sr. Director, Medicinal Chemistry About Us
Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases and immune mediated diseases. Jnana’s wholly owned lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, a highly experienced management team, and the backing of leading life science investors Bain Capital Life Sciences, RA Capital Management, Polaris Partners, Versant Ventures, Avalon Ventures, Pfizer Ventures, and AbbVie Ventures. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn .
About the Opportunity
Jnana Therapeutics is seeking an exceptional Director/Senior Director, Medicinal Chemist to join our internal chemistry group focused on drug discovery programs for hard-to-drug targets. This individual will play a critical role in developing our platform and executing on drug discovery programs. Through small molecule screening using our novel and proprietary chemoproteomics RAPID platform, our research aims to identify novel small molecules against these challenging targets to interrogate target biology and ultimately to develop drug candidates that can provide clinical value to patients.
Responsibilities
Provide medicinal chemistry leadership and program expertise to drive and lead programs from hit generation to clinical candidate selection using state of the art design principles and strategies
Provide key strategic input to new target identification, hit-generation, lead optimization and clinical development plans
Lead a team of highly skilled Medicinal Chemists and cultivate strong cross-functional working relationships
Work closely with external chemistry CRO teams to synthesize and screen target molecules
Work collaboratively across scientific disciplines on multiple projects
Proactively engage in brainstorming and the generation of new ideas across projects
Assist in preparing patent applications and publications
Help to build and expand an innovative platform for drug discovery and internal chemistry capabilities
Preferred Qualifications & Past Experience
Ph.D. and post-doctoral experience in Organic Chemistry, Medicinal Chemistry, or closely related field with at least 10 years of industry experience successfully leading medicinal chemistry efforts in drug discovery into clinical development
Strong commitment to excellence and passion for drug discovery and development
Highly organized, detailed-oriented with excellent communication skills and passion for working in multidisciplinary teams
Demonstrated track-record of mentoring, developing and leading direct reports
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Director/Sr. Director jobs in Boston, MA, United States
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